Native Proteins and Derivatives
Sigma Aldrich Fine Chemicals Biosciences fibronectin bovine plasma2MG
fibronectin is a glycoprotein with multiple domains. It comprises a N-terminal central binding domain and a heparin-binding domain. Bovine plasma fibronectin has polypeptide chains with disulfide linkage and corresponds to a molecular weight of 220 and 215 kDa.
Sigma Aldrich Fine Chemicals Biosciences fibronectin fITC suitable
fibronectin is purified from human plasma (Cat. No. f0895). The protein is modified to contain covalently linked fluorescein 5-isothiocyanate (Cat. No. f7250).fibronectin also known as Cold-insoluble globulin is a large glycoprotein of the extracellular matrix that is coded by fN1 gene. It is expressed in the plasma and at the cell surface. fibronectin is a ubiquitous and essential component of the extracellular matrix (ECM) and plays a vital role during tissue repair. fibronectin functions both as a regulator of cellular processes and an important scaffolding protein to maintain and direct tissue organization and ECM composition. fibronectin plays an important role in cell adhesion and spreading and affect the routes of cell migration both in vivo and in culture. Proteolytic degradation of extracellular matrix (ECM) is a critical step during cell invasion and tissue transmigration that is required for many physiological and pathological processes. Cellular structures that mediate ce
Cayman Chemical SARSCoV2B 1 1 7Alpha Va 96
Cayman’s SARS-CoV-2 (B.1.1.7, Alpha Variant) Neutralizing Antibody SimpleDetect ELISA Kit is a competitive assay that can be used for qualitative and/or semi-quantitative measurement of neutralizing antibodies in human plasma and serum. The assay has a range of 7.81-1,000 ng/ml, with a midpoint (50% B/B0) of 100-160 ng/ml, and a sensitivity (80% B/B0) of approximately 49 ng/ml.
Cayman Chemical PseudogInsenosIde F11 50mg
A ginsenoside with diverse biological activities; prevents tubular cell apoptosis, decreases in renal GPX and SOD levels, and increases in renal lipid peroxide levels in a rat model of cisplatin-induced nephrotoxicity at 10 mg/kg; reduces infarct size, brain water content, and cortical accumulation of autophagosomes in a rat model of ischemic stroke induced by permanent middle cerebral artery occlusion; inhibits morphine-induced memory impairment in the Morris water maze and development of morphine-induced conditioned place preference in mice at 4 and 8 mg/kg; reduces hippocampal AGE and MDA levels, increases hippocampal SOD activity and GSH levels, and attenuates cognitive impairment in the Morris water maze in a mouse model of D-galactose-induced mild cognitive impairment
Cayman Chemical CalpaIn InhIbItr I 5mg
A synthetic tripeptide aldehyde that acts as a potent inhibitor of cysteine proteases including calpain I (Ki = 190 nM), calpain II (Ki = 220 nM) cathepsin B (Ki = 150 nM), and cathepsin L (Ki = 500 pM); prevents the degradation of IκBα and IκBβ by the ubiquitin-proteasome complex, which blocks activation of NFκB and the production of TNF and IL-1β
ABclonal Technology APOE Rabbit mAb
The protein encoded by this gene is a major apoprotein of the chylomicron It binds to a specific liver and peripheral cell receptor and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes Mutations in this gene result in familial dysbetalipoproteinemia or type III hyperlipoproteinemia (HLP III) in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants
ILEX LIFE SCIENCES LLC Human Chorionic Gonadotropin (hCG), Native Protein (Urine), Bioactive, 2.5 mg
Our Human Chorionic Gonadotropin (hCG) is a native protein produced from a sterile preparation of placental glucoprotein urine of pregnant women and has a total Mw of 36.7 kDa. The hCG consists of 237 amino acids; 92 a.a. a-chain and 145 a.a. b-chain. Lyophilized with no additives. Free of HbsAg and antibodies to HIV and HCV. BIOLOGICAL ACTIVITY: Each lot is bioactivity tested and the IU/mg is stated on a lot-specific datasheet and vial label. Generally speaking, bioactivity ranges between 4000-6000 IU/mg. APPLICATION: Our hCG is commonly used in combination with our Pregnant Mare Serum Gonadotropin (PMSG, eCG) in superovulation protocols for production of genetically modified laboratory animals, such as GEMM by pronuclear microinjection (transgenic mouse), targeted mutations through CRISPR-Cas9 methods, and ES-cell-based gene targeting to produce knockout mice. Our hCG can be used in the generation of Xenopus laevis and X. tropicalis eggs or embryos for use in experimental models.
BioVendor, LLC Native Protein; Human,Cystatin C; Purified; Tagless; Size: 0.1mg
Native Protein; Human,Cystatin C; Purified; Tagless; Size: 0.1mg
BioVendor, LLC Human Chorionic Gonadotropin (hCG), Native Protein (10 mg)
Human Chorionic Gonadotropin (hCG) Native Protein, 10 mg. Research use only. Bioactivity approx. 5000-6000 IU/mg. Each lot is tested for biological activity which may vary with each lot. Produced from a sterile preparation of placental glucoprotein urine of pregnant women. Total MW of 36,700 Dalton. Consists of 237 amino acids, a chain-92 a.a. and b chain-145 a.a. Sterile filtered white powder, lyophilized w/ no additives. hCG is a peptide hormone used in superovulation techniques to increase the number of ovulated oocytes in lab animals. Mice are typically injected with PMSG to stimulate follicle growth and later injected with hCG to induce ovulation. hCG is made by the embryo soon after conception and later by the syncytiotrophoblast. hCG prevents the disintegration of the corpus luteum and thereby maintains progesterone production, critical for human pregnancy. hCG may affect immune tolerance of the pregnancy. Early pregnancy testing is usually based on hCG detection/measurement.
Medchemexpress LLC PLAU/uPA Rat HEK29 100ug
PLAU/uPA proteins lack conserved residues critical for feature annotation propagation suggesting potential differences in molecular interactions in plasminogen activation and fibrinolysis regulation PLAU/uPA Protein Rat (HEK293 His) is the recombinant rat-derived PLAU/uPA protein expressed by HEK293 with C-His labeled tag
ILEX LIFE SCIENCES LLC Apo Transferrin Human, Native Protein (Serum), 500 mg
Apo Transferrin Human, Native Protein (Serum) is a glycoprotein purified from human serum that has a molecular mass of approximately 77 kDa. It has a low iron content of ~9 ppm. FORMULATION: Sterile filtered white lyophilized (freeze-dried) powder. The protein (10 mg/ml) was lyophilized from 20mM NH4HC03 solution. May contain traces of buffer salts. PURITY: Greater than 98.0%. IRON CONTENT: The iron content was estimated by ICP and was found to be 9 ppm. SAFETY: Plasma from each donor has been tested and found negative for antibody to HIV-1, HIV-2, HCV, HBSAG and Syphilis. OTHER NAMES: Human ApoTransferrin, iron-free transferrin, Serotransferrin, Transferrin, Siderophilin, Beta-1-metal-binding globulin, TF, PRO1557, PRO2086, DKFZp781D0156, ATF.